CARDIOVASCULAR ENDOCRINOLOGY Endogenous Sex Hormones and Cardiovascular Disease in Men

نویسندگان

  • Majon Muller
  • Yvonne T. van der Schouw
  • Jos H. H. Thijssen
  • Diederick E. Grobbee
  • MAJON MULLER
  • JOS H. H. THIJSSEN
  • DIEDERICK E. GROBBEE
چکیده

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Endogenous sex hormones and cardiovascular disease in men.

Unlike women, men do not experience an abrupt reduction in endogenous sex hormone production. It has, however, become clear that an age-associated decrease in the levels of (bioactive) sex hormones does occur. Whether endogenous sex hormones have an impact on cardiovascular disease has for many years remained largely unknown, but during the last decade more attention has been drawn to the impor...

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Endogenous sex hormones and the prospective association with cardiovascular disease and mortality in men: the Tromsø Study.

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Prospective Population-Based Study

Plasma obtained and frozen in 1972-1974 from 1,009 white men (40-79 years old) who have been followed for 12 years was examined for endogenous sex hormone levels according to prevalent or subsequent cardiovascular disease. In these older men, no sex hormone measured (testosterone, androstenedione, estrone, or estradiol) was significantly associated with known cardiovascular disease at baseline ...

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Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor.

The vascular endothelium plays a crucial role in the regulation of vascular homeostasis by controlling vascular tone, coagulation, and inflammatory responses. These actions are exerted by endothelial factors including nitric oxide, prostacyclin, and endothelium-derived hyperpolarizing factor (EDHF). The greater incidence of cardiovascular disease (CVD) in men and postmenopausal women compared w...

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تاریخ انتشار 2003